*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RY5450000
CHEMICAL NAME           : Penicillin G, aluminum complex with
                          sulfamethoxypyridazine
LAST UPDATED            : 199712
DATA ITEMS CITED        : 16
MOLECULAR FORMULA       : C43-H45-Al-N8-O11-S3
MOLECULAR WEIGHT        : 973.12
WISWESSER LINE NOTATION : T45 ANV ESTJ CMV1R& F1 F1 GVO-AL-NSWR DZ&- CT6NNJ
                          FO1&OV- GT45 ANV ESTJ CMV1R& F1 F1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AB 109
   * Dipenicillina G-alluminio-sulfametossipiridazina
   * Dipenicillin G-aluminium-sulphamethoxypyridazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3580 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   98,453,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5720 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   98,453,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   98,453,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 4500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   98,453,1959

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 2 mg(Al)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-AUSTRALIA:TWA 2 mg(Al)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 2 mg(Al)/m3 JAN 1993
   
   OEL-DENMARK:TWA 2 mg(Al)/m3 JAN 1993
   
   OEL-FRANCE:TWA 2 mg(Al)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 2 mg(Al)/m3 JAN 1993
   
   OEL-RUSSIA:TWA 2 mg(Al)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 2 mg(Al)/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 2 mg(Al)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 2 mg(Al)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

 
                            *** END OF RECORD ***