*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : RZ9450000
CHEMICAL NAME : Pentane
CAS REGISTRY NUMBER : 109-66-0
LAST UPDATED : 199712
DATA ITEMS CITED : 37
MOLECULAR FORMULA : C5-H12
MOLECULAR WEIGHT : 72.17
WISWESSER LINE NOTATION : 5H
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Amyl hydride
* Pentan
* Pentane
* Pentanen
* Pentani
* Skellysolve A
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 364 gm/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 32(10),23,1988
TYPE OF TEST : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 325 gm/m3/2H
TOXIC EFFECTS :
Behavioral - excitement
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 58,74,1936
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 446 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc.,
2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961-
Volume(issue)/page/year: 67,566,1978
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 10 gm/kg/4W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in kidney weight
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - death
REFERENCE :
TIHEEC Toxicology and Industrial Health. (Princeton Scientific Pub. Co.,
POB 2155, Princeton, NJ 08540) V.1- 1985- Volume(issue)/page/year:
1(3),67,1985
*** REVIEWS ***
ACGIH TLV-STEL 2210 mg/m3 (750 ppm)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
ACGIH TLV-TWA 1770 mg/m3 (600 ppm)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
*** U.S. STANDARDS AND REGULATIONS ***
MSHA STANDARD-air:TWA 500 ppm (1475 mg/m3)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
3,200,1971
OSHA PEL (Gen Indu):8H TWA 1000 ppm (2950 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 500 ppm (1500 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 500 ppm (1500 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 1000 ppm (2950 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 600 ppm (1800 mg/m3);STEL 750 ppm (2250 mg/m3) JAN 1993
OEL-BELGIUM:TWA 600 ppm (1770 mg/m3);STEL 750 ppm (2210 mg/m3) JAN 1993
OEL-DENMARK:TWA 500 ppm (1500 mg/m3) JAN 1993
OEL-FINLAND:TWA 500 ppm (1500 mg/m3);STEL 625 ppm (1800 mg/m3) JAN 1993
OEL-FRANCE:TWA 600 ppm (1800 mg/m3) JAN 1993
OEL-GERMANY:TWA 1000 ppm (2950 mg/m3) JAN 1993
OEL-HUNGARY:TWA 500 mg/m3;STEL 1500 mg/m3 JAN 1993
OEL-JAPAN:TWA 300 ppm (880 mg/m3) JAN 1993
OEL-THE NETHERLANDS:TWA 600 ppm (1800 mg/m3) JAN 1993
OEL-THE PHILIPPINES:TWA 1000 ppm (2950 mg/m3) JAN 1993
OEL-POLAND:TWA 100 mg/m3 JAN 1993
OEL-RUSSIA:TWA 300 ppm;STEL 300 mg/m3 JAN 1993
OEL-SWEDEN:TWA 600 ppm (1800 mg/m3);STEL 750 ppm (2000 mg/m3) JAN 1993
OEL-SWITZERLAND:TWA 600 ppm (1800 mg/m3) JAN 1993
OEL-TURKEY:TWA 1000 ppm (2950 mg/m3) JAN 1993
OEL-UNITED KINGDOM:TWA 600 ppm (1800 mg/m3);STEL 750 ppm JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO PENTANE-air:10H TWA 120 ppm;CL 610 ppm/15M
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 54243
No. of Facilities: 3762 (estimated)
No. of Industries: 31
No. of Occupations: 22
No. of Employees: 34548 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 54243
No. of Facilities: 1935 (estimated)
No. of Industries: 24
No. of Occupations: 47
No. of Employees: 38465 (estimated)
No. of Female Employees: 10889 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
NIOSH Analytical Method, 1994: Hydrocarbons, BP 36-126 degree C, 1500
NIOSH Analytical Method, 1996: Volatile organic compound, 2549
*** END OF RECORD ***