*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SC3067000
CHEMICAL NAME           : tert-Pentyl hydroperoxide
CAS REGISTRY NUMBER     : 3425-61-4
BEILSTEIN REFERENCE NO. : 1731878
REFERENCE               : 4-01-00-01671 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C5-H12-O2
MOLECULAR WEIGHT        : 104.17
SYNONYMS/TRADE NAMES :
   * t-Amyl hydroperoxide
   * tert-Amyl hydroperoxide
   * 1,1-Dimethylpropyl hydroperoxide
   * Hydroperoxide, 1,1-dimethylpropyl
   * Trigonox TAHP
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 864 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Kidney, Ureter, Bladder - hematuria
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 22(7),51,1978
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1510 mg/m3
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - changes in lung weight
   Blood - methemoglobinemia-carboxyhemoglobin
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - cytochrome oxidases (including oxidative phosphorylation)
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 25(5),53,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Kidney, Ureter, Bladder - hematuria
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 22(7),51,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - changes in lung weight
   Blood - methemoglobinemia-carboxyhemoglobin
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - cytochrome oxidases (including oxidative phosphorylation)
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 25(5),53,1981
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1370 mg/m3
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - changes in lung weight
   Blood - methemoglobinemia-carboxyhemoglobin
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - cytochrome oxidases (including oxidative phosphorylation)
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 25(5),53,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 275 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,21,1982

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-RUSSIA:STEL 5 mg/m3;Skin JAN 1993

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***