*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SC5647000
CHEMICAL NAME           : 4-Pentyno-2',6'-xylidide, 2-(diethylamino)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 15960-90-4
LAST UPDATED            : 198212
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H24-N2-O.Cl-H
MOLECULAR WEIGHT        : 308.89
WISWESSER LINE NOTATION : 2N2&Y2UU1&VMR B1 F1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-(Diethylamino)-4-pentyno-2',6'-xylidide hydrochloride
   * 2-Diethylaminopent-4-ynoyl-2,6-xylidide hydrochloride
   * 4-Pentynamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-,  
   monohydrochloride
   * WY 21745
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 742 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 191,405,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 41 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 191,405,1971
 
                            *** END OF RECORD ***