*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SC6250000
CHEMICAL NAME           : Peptimycin
CAS REGISTRY NUMBER     : 11006-46-5
LAST UPDATED            : 199109
DATA ITEMS CITED        : 3
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
                          Natural Product
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 650 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 17,693,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds.,
   Tokyo, Univ. of Tokyo Press, 1967  Volume(issue)/page/year: -,497,1967
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 500 ug/L
REFERENCE :
   IJCPB5 International Journal of Clinical Pharmacology, Therapy and
   Toxicology.  (Dustri-Verlag Dr. Karl Feistle, Postfach 49, D-8024
   Munich-Deisenhofen, Fed. Rep. Ger.)  V.6-10, 1972-74; V.18-    1980-
   Volume(issue)/page/year: 9,250,1974
 
                            *** END OF RECORD ***