*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SF7960500
CHEMICAL NAME           : Phenanthridinium, 3,8-diamino-5-methyl-6-phenyl-,
                          bromide
CAS REGISTRY NUMBER     : 518-67-2
LAST UPDATED            : 199512
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C20-H18-N3.Br
MOLECULAR WEIGHT        : 380.32
WISWESSER LINE NOTATION : T B666 HKJ EZ H1 IR& LZ &E
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6C46
   * 2,7-Diamino-10-methyl-9-phenylphenanthridinium bromide
   * 3,8-Diamino-5-methyl-6-phenylphenanthridinium bromide
   * Dimidium bromide
   * Phenanthridinium 1553
   * Phenanthridinium compound 1553
   * Trypadine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 61 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 1,65,1946
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 5,261,1950
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 10 mg/kg/5D-I
TOXIC EFFECTS :
   Liver - fatty liver degeneration
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 1,65,1946

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X6236
       No. of Facilities: 34 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 67 (estimated)
       No. of Female Employees: 34 (estimated)

 
                            *** END OF RECORD ***