*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SI0580000
CHEMICAL NAME           : Phenethylamine, alpha-methyl-3,4-(methylenedioxy)-
CAS REGISTRY NUMBER     : 4764-17-4
BEILSTEIN REFERENCE NO. : 0150196
REFERENCE               : 5-19-08-00417 (Beilstein Handbook Reference)
LAST UPDATED            : 199706
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C10-H13-N-O2
MOLECULAR WEIGHT        : 179.24
WISWESSER LINE NOTATION : T56 BO DO CHJ G1YZ1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,3-Benzodioxole-5-ethanamine, alpha-methyl-
   * MDA (pharmaceutical)
   * alpha-Methyl-1,3-benzodioxole-5-ethanamine
   * Methylenedioxyamphetamine
   * 3,4-Methylenedioxy-amphetamine
   * alpha-Methyl-3,4-(methylenedioxy)phenethylamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 13300 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - convulsions or effect on seizure threshold
   Skin and Appendages - hair
REFERENCE :
   CTOXAO Clinical Toxicology.  (New York, NY)  V.1-18, 1968-81.  For publisher
   information, see JTCTDW.  Volume(issue)/page/year: 6,193,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 58300 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - excitement
   Skin and Appendages - hair
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 214,133,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 31100 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - convulsions or effect on seizure threshold
   Skin and Appendages - hair
REFERENCE :
   TRBMAV Texas Reports on Biology and Medicine.  (Galveston, TX)  V.1-41(2),
   1943-81/82.  Discontinued.  Volume(issue)/page/year: 33,610,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 6 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,798,1986

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   CTOXAO Clinical Toxicology.  (New York, NY)  V.1-18, 1968-81.  For publisher
   information, see JTCTDW.  Volume(issue)/page/year: 6,45,1973

 
                            *** END OF RECORD ***