*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SI1950000
CHEMICAL NAME           : Phenethylamine, alpha-methyl-p-(trifluoromethyl)-,
                          (+-)-, hydrochloride
CAS REGISTRY NUMBER     : 882-00-8
LAST UPDATED            : 199506
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H12-F3-N.Cl-H
MOLECULAR WEIGHT        : 239.69
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzeneethanamine, alpha-methyl-4-(trifluoromethyl)-, hydrochloride
   * (+-)-alpha-Methyl-p-(trifluoromethyl)phenethylamine
   * P-1727
   * DL-(p-Trifluoromethylphenyl)isopropylamine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3600 mg/kg/12W-I
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - retinal changes (pigmentary
   depositions, retinitis, other)
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   5,298,1963
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 7800 mg/kg/26W-I
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - retinal changes (pigmentary
   depositions, retinitis, other)
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   5,298,1963
 
                            *** END OF RECORD ***