*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SI3675000
CHEMICAL NAME           : Phenethylamine, N,alpha,alpha-trimethyl-
CAS REGISTRY NUMBER     : 100-92-5
BEILSTEIN REFERENCE NO. : 1363850
REFERENCE               : 4-12-00-02820 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C11-H17-N
MOLECULAR WEIGHT        : 163.29
WISWESSER LINE NOTATION : 1MX1&1&1R
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Mefenterdrin
   * Mefentermin
   * Mephenterdrine
   * Mephenterdrinum
   * Mephentermine
   * Mephetedrine
   * Mephine
   * 2-Methylamino-2-methyl-1-phenylpropane
   * 2-Methyl-2-methylamino-1-phenylpropane
   * N-Methyl-omega-phenyl-t-butylamine
   * N,alpha,alpha-Trimethylbenzeneethanamine
   * N,alpha,alpha-Trimethylphenethylamine
   * N,alpha,alpha-Trimethyl-beta-phenethylamine
   * Vialin
   * WY-585
   * Wyamine
   * Wyfentermina
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 85 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - tremor
   Behavioral - excitement
REFERENCE :
   ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und
   Laboratoriums-diagnostik.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr.
   18, 102 Berlin, Ger. Dem. Rep.)  V.109-    1970-  Volume(issue)/page/year:
   111,169,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - tremor
   Behavioral - excitement
REFERENCE :
   ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und
   Laboratoriums-diagnostik.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr.
   18, 102 Berlin, Ger. Dem. Rep.)  V.109-    1970-  Volume(issue)/page/year:
   111,169,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 57 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - tremor
   Behavioral - excitement
REFERENCE :
   ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und
   Laboratoriums-diagnostik.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr.
   18, 102 Berlin, Ger. Dem. Rep.)  V.109-    1970-  Volume(issue)/page/year:
   111,169,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 89 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - tremor
   Behavioral - excitement
REFERENCE :
   ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und
   Laboratoriums-diagnostik.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr.
   18, 102 Berlin, Ger. Dem. Rep.)  V.109-    1970-  Volume(issue)/page/year:
   111,169,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 43 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - tremor
   Behavioral - excitement
REFERENCE :
   ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und
   Laboratoriums-diagnostik.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr.
   18, 102 Berlin, Ger. Dem. Rep.)  V.109-    1970-  Volume(issue)/page/year:
   111,169,1972
 
                            *** END OF RECORD ***