*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SJ7781100
CHEMICAL NAME           : Phenol, 2-((bis(2-chloroethyl)amino)methyl)-4-nitro-
CAS REGISTRY NUMBER     : 56537-91-8
BEILSTEIN REFERENCE NO. : 2992924
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H14-Cl2-N2-O3
MOLECULAR WEIGHT        : 293.17
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Bis(2-chloroethyl)aminomethyl-4-hydroxynitrobenzene
   * 2-((Bis(2-chloroethyl)amino)methyl)-4-nitrophenol
   * 2-Di(beta-cloretil)-aminometil-4-nitrofenol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   RCBUAU Revista de Chimie (Bucharest).  (Rompresfilatelia, POB 12-201,
   Bucharest, Romania) V.1-    1950-  Volume(issue)/page/year: 30,1073,1979
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 35 mg/kg
SEX/DURATION            : female 1-7 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   IJMRAQ Indian Journal of Medical Research.  (Indian Council of Medical
   Research, Ansari Nagar, New Delhi 110 029, India)  V.1-    1913-
   Volume(issue)/page/year: 64,244,1976
 
                            *** END OF RECORD ***