*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SL0532000
CHEMICAL NAME           : Phenol, 2-(2,4-dichlorophenoxy)-4,5,6-trichloro-
CAS REGISTRY NUMBER     : 53555-01-4
BEILSTEIN REFERENCE NO. : 4522298
LAST UPDATED            : 199612
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C12-H5-Cl5-O2
MOLECULAR WEIGHT        : 358.42
WISWESSER LINE NOTATION : QR BG CG DG FOR BG DG
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Cl5-Predioxin
   * 2-(2,4-Dichlorophenoxy)-4,5,6-trichlorophenol
   * 6-(2,4-Dichlorophenoxy)-2,3,4-trichlorophenol
   * 2',3,4,4',5-Pentachloro-2-hydroxydiphenyl ether
   * Phenol, 6-(2,4-dichlorophenoxy)-2,3,4-trichloro-
   * 4,5,6-Trichloro-2-(2,4-dichlorophenoxy)phenol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 170 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - irritability
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 12,245,1983
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 50 mg/L
REFERENCE :
   EVSRBT Environmental Science Research.  (Plenum Pub. Corp., 233 Spring St.,
   New York, NY 10013) V.1-    1972-  Volume(issue)/page/year: 12,325,1978
 
TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 50 mg/L
REFERENCE :
   EVSRBT Environmental Science Research.  (Plenum Pub. Corp., 233 Spring St.,
   New York, NY 10013) V.1-    1972-  Volume(issue)/page/year: 12,325,1978
 
TYPE OF TEST            : Specific locus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
REFERENCE :
   EVSRBT Environmental Science Research.  (Plenum Pub. Corp., 233 Spring St.,
   New York, NY 10013) V.1-    1972-  Volume(issue)/page/year: 12,325,1978

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: S cerevisiae-forward mutation; S
   cerevisiae-homozygosis
   
   EPA GENETOX PROGRAM 1988, Negative: S cerevisiae gene conversion
   
   EPA GENETOX PROGRAM 1988, Inconclusive: Mouse spot test

 
                            *** END OF RECORD ***