*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : SL3070000 CHEMICAL NAME : Phenol, p-(2,4-dinitroanilino)- CAS REGISTRY NUMBER : 119-15-3 BEILSTEIN REFERENCE NO. : 2223171 REFERENCE : 4-13-00-01052 (Beilstein Handbook Reference) LAST UPDATED : 199703 DATA ITEMS CITED : 9 MOLECULAR FORMULA : C12-H9-N3-O5 MOLECULAR WEIGHT : 275.24 WISWESSER LINE NOTATION : WNR CNW DMR DQ COMPOUND DESCRIPTOR : Mutagen SYNONYMS/TRADE NAMES : * Acetamine Yellow 2R * Acetoquinone Light Yellow 2RZ * Amacel Yellow RR * Celliton Fast Yellow RR * Cilla Fast Yellow RR * C.I. 10345 * C.I. Disperse Yellow 1 * C.I. Solvent Yellow 52 * 2,4-Dinitro-p-hydroxydiphenylamine * Disperse Fast Yellow 2K * Disperse Yellow R * Dispersol Fast Yellow A * Dispersol Printing Yellow A * Dispersol Yellow B-A * Disperse Yellow Stable 2K * Fast Disperse Yellow 2K * Fenacet Fast Yellow 2R * Kayalon Fast Yellow RR * Microsetile Yellow 2R * Nyloquinone Yellow 2R * Perliton Yellow RR * Permanent Yellow 2K * Reliton Yellow R * Serisol Fast Yellow A * Setacyl Yellow P-BS * SRA Golden Yellow VIII * Supracet Fast Yellow 2R * Supracet Yellow RR * Synten Yellow P 2R * Zolcien syntenowa P-2R *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 15610 mg/kg TOXIC EFFECTS : Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea REFERENCE : BCTKAG Bromatologia i Chemia Toksykologiczna. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.4- 1971- Volume(issue)/page/year: 21,65,1988 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5230 mg/kg TOXIC EFFECTS : Behavioral - food intake (animal) Behavioral - muscle weakness Kidney, Ureter, Bladder - other changes in urine composition REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 52(11),94,1987 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 6550 mg/kg TOXIC EFFECTS : Behavioral - food intake (animal) Behavioral - muscle weakness Kidney, Ureter, Bladder - other changes in urine composition REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 52(11),94,1987 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 2500 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - cyanosis REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 40(10),114,1975 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 60 gm/kg/30D-I TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 52(11),94,1987 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 33 ug/plate REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0745 No. of Facilities: 16 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 741 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0745 No. of Facilities: 55 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 1125 (estimated) No. of Female Employees: 78 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***