*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SL3070000
CHEMICAL NAME           : Phenol, p-(2,4-dinitroanilino)-
CAS REGISTRY NUMBER     : 119-15-3
BEILSTEIN REFERENCE NO. : 2223171
REFERENCE               : 4-13-00-01052 (Beilstein Handbook Reference)
LAST UPDATED            : 199703
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C12-H9-N3-O5
MOLECULAR WEIGHT        : 275.24
WISWESSER LINE NOTATION : WNR CNW DMR DQ
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Acetamine Yellow 2R
   * Acetoquinone Light Yellow 2RZ
   * Amacel Yellow RR
   * Celliton Fast Yellow RR
   * Cilla Fast Yellow RR
   * C.I. 10345
   * C.I. Disperse Yellow 1
   * C.I. Solvent Yellow 52
   * 2,4-Dinitro-p-hydroxydiphenylamine
   * Disperse Fast Yellow 2K
   * Disperse Yellow R
   * Dispersol Fast Yellow A
   * Dispersol Printing Yellow A
   * Dispersol Yellow B-A
   * Disperse Yellow Stable 2K
   * Fast Disperse Yellow 2K
   * Fenacet Fast Yellow 2R
   * Kayalon Fast Yellow RR
   * Microsetile Yellow 2R
   * Nyloquinone Yellow 2R
   * Perliton Yellow RR
   * Permanent Yellow 2K
   * Reliton Yellow R
   * Serisol Fast Yellow A
   * Setacyl Yellow P-BS
   * SRA Golden Yellow VIII
   * Supracet Fast Yellow 2R
   * Supracet Yellow RR
   * Synten Yellow P 2R
   * Zolcien syntenowa P-2R
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 15610 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   BCTKAG Bromatologia i Chemia Toksykologiczna.  (Ars Polona, POB 1001, 00-068
   Warsaw 1, Poland) V.4-    1971-  Volume(issue)/page/year: 21,65,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5230 mg/kg
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Behavioral - muscle weakness
   Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(11),94,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6550 mg/kg
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Behavioral - muscle weakness
   Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(11),94,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 40(10),114,1975
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 60 gm/kg/30D-I
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Blood - pigmented or nucleated red blood cells
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(11),94,1987
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 33 ug/plate
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   11(Suppl 12),1,1988

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - T0745
       No. of Facilities: 16 (estimated)
       No. of Industries: 1
       No. of Occupations: 4
       No. of Employees: 741 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - T0745
       No. of Facilities: 55 (estimated)
       No. of Industries: 2
       No. of Occupations: 5
       No. of Employees: 1125 (estimated)
       No. of Female Employees: 78 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***