*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SL3785000
CHEMICAL NAME           : Phenol, 4-(3-ethenyl-3,7-dimethyl-1,6-octadienyl)-,
                          (S-(E))-
CAS REGISTRY NUMBER     : 10309-37-2
LAST UPDATED            : 199801
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C18-H24-O
MOLECULAR WEIGHT        : 256.42
WISWESSER LINE NOTATION : QR D1U1X1&1U1&3UY1&1
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Bakuchiol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MZHUDX Mikrobiologicheskii Zhurnal (Kiev).  Journal of Microbiology.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.40-    1978-
   Volume(issue)/page/year: 42,646,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2560 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MZHUDX Mikrobiologicheskii Zhurnal (Kiev).  Journal of Microbiology.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.40-    1978-
   Volume(issue)/page/year: 42,646,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 94 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MZHUDX Mikrobiologicheskii Zhurnal (Kiev).  Journal of Microbiology.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.40-    1978-
   Volume(issue)/page/year: 42,646,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 31 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MZHUDX Mikrobiologicheskii Zhurnal (Kiev).  Journal of Microbiology.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.40-    1978-
   Volume(issue)/page/year: 42,646,1980
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 mg/kg/10D-I
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - death
REFERENCE :
   MZHUDX Mikrobiologicheskii Zhurnal (Kiev).  Journal of Microbiology.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.40-    1978-
   Volume(issue)/page/year: 42,646,1980
 
                            *** END OF RECORD ***