*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : SL8400000 CHEMICAL NAME : Phenol, p-(2-(methylamino)propyl)- CAS REGISTRY NUMBER : 370-14-9 LAST UPDATED : 199603 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C10-H15-N-O MOLECULAR WEIGHT : 165.26 WISWESSER LINE NOTATION : QR D1Y1&M1 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Epifen * Foledrin * p-Hydroxy-N,alpha-dimethylphenethylamine * p-Hydroxymethamphetamine * p-Hydroxy-N-methylbenzedrine * beta-(p-Hydroxyphenyl)isopropylmethylamine * alpha-(p-Hydroxyphenyl)-beta-methylaminopropane * 1-(p-Hydroxyphenyl)-2-methylaminopropane * Isodrine * Isodrinum * Knoll H75 * p-(2-Methylaminopropyl)phenol * N-Methylparedrine * beta(p-Oxy-phenyl)isopropylmethylamin * 1-(p-Oxyphenyl)-2-methylaminopropan * alpha-(p-Oxyphenyl)-beta-methyl aminopropane * Paredrinol * Phenethylamine, p-hydroxy-N,alpha-dimethyl- * Pholedrine * Pholetone * Pressitan * Promethin * Prometin * Pulsotyl * Stimatone * Sympropamin * Syncordan * Terapinyl * Varitol * Veritain * Veritol *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Behavioral - changes in psychophysiological tests REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 159,442,1966 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,101,1948 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 119 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 3,328,1953 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 195,647,1940 *** END OF RECORD ***