*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : SM0175000
CHEMICAL NAME : Phenol, 2,2'-methylenebis(4-chloro-
CAS REGISTRY NUMBER : 97-23-4
BEILSTEIN REFERENCE NO. : 1884514
REFERENCE : 4-06-00-06658 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 15
MOLECULAR FORMULA : C13-H10-Cl2-O2
MOLECULAR WEIGHT : 269.13
WISWESSER LINE NOTATION : QR DG B1R BQ EG
COMPOUND DESCRIPTOR : Agricultural Chemical
Drug
Mutagen
Primary Irritant
SYNONYMS/TRADE NAMES :
* Anthiphen
* Antifen
* Bis(5-chlor-2-hydroxyphenyl)-methan
* Bis(5-chloro-2-hydroxyphenyl)methane
* Bis-2-hydroxy-5-chlorfenylmethan
* Bis(2-hydroxy-5-chlorophenyl)methane
* Cordocel
* DDDM
* Dicestal
* Dichloorfeen
* 5,5'-Dichloro-2,2'-dihydroxydiphenylmethane
* Di-(5-chloro-2-hydroxyphenyl)methane
* Dichlorofen
* 4,4'-Dichloro-2,2'-methylenediphenol
* Dichlorophen
* Dichlorophen B
* Dichlorophene
* Dichlorphen
* Didroxan
* Didroxane
* Difentan
* 2,2'-Dihydroxy-5,5'-dichlorodiphenylmethane
* Diphenthane 70
* Embephen
* Fungicide GM
* Fungicide M
* Gefir
* Gingivit
* Giv Gard G 4-40
* Hyosan
* Korium
* O,O-Methyleen-bis(4-chloorfenol)
* 2,2'-Methylenebis(4-chlorophenol)
* O,O-Metilen-bis(4-cloro-fenolo)
* Panacide
* Parabis
* Plath-lyse
* Prevental
* Preventol GD
* Preventol GDC
* Sindar G 4
* Super mosstox
* Taeniatol
* Teniathane
* Teniatol
* Teniotol
* Vermithana
* Wespuril
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,533,1986
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 50 ug/24H
REACTION SEVERITY : Severe
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,533,1986
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1506 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
7,299,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 17 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CRTXB2 CRC Critical Reviews in Toxicology. (CRC Press, Inc., 2000 Corporate
Blvd., NW, Boca Raton, FL 33431) V.1- 1971- Volume(issue)/page/year:
2,445,1974
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 96,238,1949
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCOC** Pesticide Chemicals Official Compendium, Association of the American
Pesticide Control Officials, Inc., 1966. (Topeka, KS)
Volume(issue)/page/year: -,361,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College
Science Pub., 1969 Volume(issue)/page/year: 5,75,1976
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 50 nmol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 90,91,1981
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 150 ug/plate
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E.
11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year:
19(Suppl 21),2,1992
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84582
No. of Facilities: 855 (estimated)
No. of Industries: 7
No. of Occupations: 7
No. of Employees: 3398 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 84582
No. of Facilities: 441 (estimated)
No. of Industries: 4
No. of Occupations: 8
No. of Employees: 4290 (estimated)
No. of Female Employees: 2030 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***