*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BP7525000
CHEMICAL NAME           : Ammonium, diethyl(2-hydroxyethyl)methyl-, bromide,
                          alpha-cyclopentyl-2-thiopheneglycolate
CAS REGISTRY NUMBER     : 60-44-6
LAST UPDATED            : 199109
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C18-H30-N-O3-S.Br
MOLECULAR WEIGHT        : 420.46
WISWESSER LINE NOTATION : T5SJ BXQVO2K2&2&1&- AL5TJ &Q &E
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * alpha-Cyclopentyl-2-thiopheneglycolate  
   diethyl(2-hydroxyethyl)methylammonium bromide
   * 2-Diethylaminoethyl 2-cyclopentyl-2-(2-thienyl)hydroxyacetate  
   methobromide
   * 2-Diethylaminoethyl alpha-cyclopentyl-2-thiopheneglycolate methobromide
   * Diethyl(2-hydroxyethyl)methylammonium bromide,  
   alpha-cyclopentyl-2-thiopeneglycolate
   * Ethanaminium,  
   2-((cyclopentylhydroxy-2-thienylacetyl)oxy)-N,N-diethyl-N-methyl-,   bromide
   * Monodral
   * Monodral bromide
   * Penthienate
   * Penthienate bromide
   * WIN 4369
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2080 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 110,282,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 110,282,1954
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 99 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 151,614,1957
 
                            *** END OF RECORD ***