*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : BP6825000 CHEMICAL NAME : Ammonium, (4-(p-(diethylamino)-alpha-phenylbenzylidene)-2,5-cyc lohexadien-1-ylidene) diethyl-,sulfate (1:1) CAS REGISTRY NUMBER : 633-03-4 OTHER CAS REGISTRY NOS. : 56730-57-5 LAST UPDATED : 199706 DATA ITEMS CITED : 12 MOLECULAR FORMULA : C27-H33-N2.H-O4-S MOLECULAR WEIGHT : 482.69 WISWESSER LINE NOTATION : L6Y DYJ AUYR&R DN2&2& DUK2&2 &Q &S-O4 COMPOUND DESCRIPTOR : Drug Mutagen Primary Irritant SYNONYMS/TRADE NAMES : * ADC Brilliant Green Crystals * Aizen Diamond Green GH * Aizen Malachite Green GH * Astra Diamond Green GX * Avon Green A-4379 * Basic Bright Green * Basic Bright Green Sulfate * Basic Brilliant Green * Basic Green 1 * Basic Green V * Brilliant Green * Brilliant Green Aseptic * Brilliant Green B * Brilliant Green B.P. * Brilliant Green BP Crystals * Brilliant Green BPC * Brilliant Green Crystals * Brilliant Green Crystals H * Brilliant Green DSC * Brilliant Green G * Brilliant Green GX * Brilliant Green Lake * Brilliant Green P * Brilliant Green Special * Brilliant Green Sulfate * Brilliant Green WP Crystals * Brilliant Green Y * Brilliant Green YN * Brilliant Green YNS * Brilliant-grun * Brilliant Lake Green Y * Brilliant Tungstate Green Toner GT-288 * Calcozine Brilliant Green G * C.I. 42040 * C.I. Basic Green 1 * C.I. Basic Green 1, sulfate (1:1) * Deorlene Green JJO * Diamond Green G * Ethyl Green * Fast Green J * Fast Green JJO * 12415 Green * Green EN * Hidaco Brilliant Green * Malachite Green G * Mitsui Brilliant Green GX * Solid Green * Tertrophene Brilliant Green G * Tokyo Aniline Brilliant Green * Zelen brilantni * Zelen malachitova G * Zelen smaragdova * Zelen zasadita 1 *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Human DOSE/DURATION : 2 mg/2D (Intermittent) REACTION SEVERITY : Mild REFERENCE : ADVEA4 Acta Dermato-Venereologica. (Almqvist & Wiksell, POB 45150, S-10430 Stockholm, Sweden) V.1- 1920- Volume(issue)/page/year: 52,55,1972 TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 6 mg/3D (Intermittent) REFERENCE : ADVEA4 Acta Dermato-Venereologica. (Almqvist & Wiksell, POB 45150, S-10430 Stockholm, Sweden) V.1- 1920- Volume(issue)/page/year: 52,55,1972 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 10 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - emphysema Gastrointestinal - necrotic changes Liver - other changes REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 7(2),54,1963 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 8 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - acute pulmonary edema REFERENCE : PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 31,825,1934 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - acute pulmonary edema REFERENCE : PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 31,825,1934 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - acute pulmonary edema REFERENCE : PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 31,825,1934 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 3 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - acute pulmonary edema REFERENCE : PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 31,825,1934 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 104 mg/m3/6W-I TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 7(2),54,1963 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Yeast - Saccharomyces cerevisiae DOSE/DURATION : 100 ug/L REFERENCE : VINIT* Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii (VINITI). All-Union Institute of Scientific and Technical Information. (Moscow, USSR) Use information broker to obtain publications. Volume(issue)/page/year: #542-84 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2187 No. of Facilities: 581 (estimated) No. of Industries: 12 No. of Occupations: 14 No. of Employees: 7268 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2187 No. of Facilities: 1486 (estimated) No. of Industries: 16 No. of Occupations: 22 No. of Employees: 43142 (estimated) No. of Female Employees: 29395 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***