*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BP6825000
CHEMICAL NAME           : Ammonium,
                          (4-(p-(diethylamino)-alpha-phenylbenzylidene)-2,5-cyc
                          lohexadien-1-ylidene) diethyl-,sulfate (1:1)
CAS REGISTRY NUMBER     : 633-03-4
OTHER CAS REGISTRY NOS. : 56730-57-5
LAST UPDATED            : 199706
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : C27-H33-N2.H-O4-S
MOLECULAR WEIGHT        : 482.69
WISWESSER LINE NOTATION : L6Y DYJ AUYR&R DN2&2& DUK2&2 &Q &S-O4
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * ADC Brilliant Green Crystals
   * Aizen Diamond Green GH
   * Aizen Malachite Green GH
   * Astra Diamond Green GX
   * Avon Green A-4379
   * Basic Bright Green
   * Basic Bright Green Sulfate
   * Basic Brilliant Green
   * Basic Green 1
   * Basic Green V
   * Brilliant Green
   * Brilliant Green Aseptic
   * Brilliant Green B
   * Brilliant Green B.P.
   * Brilliant Green BP Crystals
   * Brilliant Green BPC
   * Brilliant Green Crystals
   * Brilliant Green Crystals H
   * Brilliant Green DSC
   * Brilliant Green G
   * Brilliant Green GX
   * Brilliant Green Lake
   * Brilliant Green P
   * Brilliant Green Special
   * Brilliant Green Sulfate
   * Brilliant Green WP Crystals
   * Brilliant Green Y
   * Brilliant Green YN
   * Brilliant Green YNS
   * Brilliant-grun
   * Brilliant Lake Green Y
   * Brilliant Tungstate Green Toner GT-288
   * Calcozine Brilliant Green G
   * C.I. 42040
   * C.I. Basic Green 1
   * C.I. Basic Green 1, sulfate (1:1)
   * Deorlene Green JJO
   * Diamond Green G
   * Ethyl Green
   * Fast Green J
   * Fast Green JJO
   * 12415 Green
   * Green EN
   * Hidaco Brilliant Green
   * Malachite Green G
   * Mitsui Brilliant Green GX
   * Solid Green
   * Tertrophene Brilliant Green G
   * Tokyo Aniline Brilliant Green
   * Zelen brilantni
   * Zelen malachitova G
   * Zelen smaragdova
   * Zelen zasadita 1
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Human
DOSE/DURATION           : 2 mg/2D (Intermittent)
REACTION SEVERITY       : Mild
REFERENCE :
   ADVEA4 Acta Dermato-Venereologica.  (Almqvist & Wiksell, POB 45150, S-10430
   Stockholm, Sweden) V.1-    1920-  Volume(issue)/page/year: 52,55,1972
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 6 mg/3D (Intermittent)
REFERENCE :
   ADVEA4 Acta Dermato-Venereologica.  (Almqvist & Wiksell, POB 45150, S-10430
   Stockholm, Sweden) V.1-    1920-  Volume(issue)/page/year: 52,55,1972
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - emphysema
   Gastrointestinal - necrotic changes
   Liver - other changes
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 7(2),54,1963
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 31,825,1934
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 31,825,1934
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 31,825,1934
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 3 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 31,825,1934
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 104 mg/m3/6W-I
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - death
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 7(2),54,1963
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 100 ug/L
REFERENCE :
   VINIT* Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii (VINITI).
   All-Union Institute of Scientific and Technical Information.  (Moscow, USSR)
    Use information broker to obtain publications. Volume(issue)/page/year:
   #542-84

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M2187
       No. of Facilities: 581 (estimated)
       No. of Industries: 12
       No. of Occupations: 14
       No. of Employees: 7268 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M2187
       No. of Facilities: 1486 (estimated)
       No. of Industries: 16
       No. of Occupations: 22
       No. of Employees: 43142 (estimated)
       No. of Female Employees: 29395 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***