*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BQ5775000
CHEMICAL NAME           : Ammonium, ethyl(2-hydroxyethyl)dimethyl-,
                          dibutylcarbamate (ester), sulfate (2:1)
CAS REGISTRY NUMBER     : 532-49-0
LAST UPDATED            : 199009
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C30-H66-N4-O4.O4-S
MOLECULAR WEIGHT        : 643.06
WISWESSER LINE NOTATION : 4N4&VO2K2&1&1 &Q &S-O4
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ammonium, ethyl(2-hydroxyethyl)dimethyl-, sulfate (salt),  
   bis(dibutylcarbamate)
   * Dibulinesulfat
   * Dibuline sulfate
   * Dibutoline
   * Dibutoline sulfate
   * Di-n-butyl-carbamylcholine sulphate
   * (2-Dibutylcarbamyloxyethyl)-dimethylethylammonium sulfate
   * Dimethyl-ethyl-beta-hydroxyethyl-ammonium-sulfate di-n-butylcarbamate
   * Dimethylethyl-beta-hydroxyethylammonium sulfate dibutylurethan
   * Ethanaminium, 2-(((dibutylamino)carbonyl)oxy)-N-ethyl-N,N-dimethyl-,  
   sulfate (2:1)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 22 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 84,105,1945
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 49 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)
 
                            *** END OF RECORD ***