*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BP6832000
CHEMICAL NAME           : Ammonium,
                          (6-(diethylamino)-3H-xanthen-3-ylidene)diethyl-,
                          chloride
CAS REGISTRY NUMBER     : 2150-48-3
LAST UPDATED            : 199701
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C21-H27-N2-O.Cl
MOLECULAR WEIGHT        : 358.95
WISWESSER LINE NOTATION : T C666 BO EYJ EUK2&2 MN2&2 &G
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Ammonium, diethyl(6-(diethylamino)-3H-xanthen-3-ylidene)-, chloride
   * C.I. 45010
   * (6-(Diethylamino)-3H-xanthen-3-ylidine)diethylammonium chloride
   * N-(6-(Diethylamino)-3H-xanthen-3-ylidine)-N-ethylethanaminium chloride
   * E tetraethylpyronin
   * Ethanaminium, N-(6-(diethylamino)-3H-xanthen-3-ylidene)-N-ethyl-,  
   chloride
   * NSC 44690
   * Pyronin B
   * Pyronine B
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 15100 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCISP* National Cancer Institute Screening Program Data Summary,
   Developmental Therapeutics Program. (Bethesda, MD 20205)
   Volume(issue)/page/year: JAN1986
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 20 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 89,95,1981
 
TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 1000 ppm
REFERENCE :
   AMNTA4 American Naturalist.  (Univ. of Chicago Press, Journals Div., POB
   37005, Chicago, IL 60637) V.1-    1867-  Volume(issue)/page/year:
   87,295,1953

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X3951
       No. of Facilities: 32 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 162 (estimated)
       No. of Female Employees: 124 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: D melanogaster Sex-linked lethal
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***