*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : BP6832000 CHEMICAL NAME : Ammonium, (6-(diethylamino)-3H-xanthen-3-ylidene)diethyl-, chloride CAS REGISTRY NUMBER : 2150-48-3 LAST UPDATED : 199701 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C21-H27-N2-O.Cl MOLECULAR WEIGHT : 358.95 WISWESSER LINE NOTATION : T C666 BO EYJ EUK2&2 MN2&2 &G COMPOUND DESCRIPTOR : Mutagen SYNONYMS/TRADE NAMES : * Ammonium, diethyl(6-(diethylamino)-3H-xanthen-3-ylidene)-, chloride * C.I. 45010 * (6-(Diethylamino)-3H-xanthen-3-ylidine)diethylammonium chloride * N-(6-(Diethylamino)-3H-xanthen-3-ylidine)-N-ethylethanaminium chloride * E tetraethylpyronin * Ethanaminium, N-(6-(diethylamino)-3H-xanthen-3-ylidene)-N-ethyl-, chloride * NSC 44690 * Pyronin B * Pyronine B *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 15100 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986 ** MUTATION DATA ** TYPE OF TEST : DNA adduct TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 20 umol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981 TYPE OF TEST : Sex chromosome loss and nondisjunction ROUTE OF EXPOSURE : Oral TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 1000 ppm REFERENCE : AMNTA4 American Naturalist. (Univ. of Chicago Press, Journals Div., POB 37005, Chicago, IL 60637) V.1- 1867- Volume(issue)/page/year: 87,295,1953 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3951 No. of Facilities: 32 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 162 (estimated) No. of Female Employees: 124 (estimated) *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Positive: D melanogaster Sex-linked lethal EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***