*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BR0820000
CHEMICAL NAME           : Ammonium, (4-hydroxy-o-cumenyl)trimethyl-, iodide,
                          dimethylcarbamate
CAS REGISTRY NUMBER     : 63981-53-3
LAST UPDATED            : 199203
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C15-H25-N2-O2.I
MOLECULAR WEIGHT        : 392.32
WISWESSER LINE NOTATION : 1Y1&R COVN1&1 FK1&1&1 &Q &I
SYNONYMS/TRADE NAMES :
   * Ammonium, ((4-(N,N-dimethylcarbamoyloxy)-2-isopropyl)phenyl)trimethyl-,  
   iodide
   * Ammonium, (N-(2-isopropyl-4-dimethylcarbamoyloxy)phenyl)trimethyl-,  
   iodide
   * Carbamic acid, N,N-dimethyl-, 4-dimethylamino-5-isopropylphenyl ester,  
   methiodide
   * Carbamic acid, dimethyl-, ((4-trimethylammonio)-3-isopropyl)phenyl ester, 
    iodide
   * SB-8
   * TL-599
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 ug/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-508
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 168 ug/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-508
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JACSAT Journal of the American Chemical Society.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1879-  Volume(issue)/page/year: 63,308,1941
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 200 ug/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-508
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 300 ug/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-508
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 200 ug/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-508
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 100 ug/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-508
 
                            *** END OF RECORD ***