*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : SM8397000 CHEMICAL NAME : Phenolphthalein, 3',3'',5',5''-tetraiodo- CAS REGISTRY NUMBER : 386-17-4 BEILSTEIN REFERENCE NO. : 0351654 REFERENCE : 4-18-00-01949 (Beilstein Handbook Reference) LAST UPDATED : 199706 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C20-H10-I4-O4 MOLECULAR WEIGHT : 821.90 SYNONYMS/TRADE NAMES : * Iodophene * 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxy-3,5-diiodophenyl)- * 3',3'',5',5''-Tetraiodophenolphthalein *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2800 mg/kg TOXIC EFFECTS : Behavioral - muscle weakness Behavioral - muscle contraction or spasticity REFERENCE : KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 20,125,1941 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 310 mg/kg TOXIC EFFECTS : Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - dyspnea REFERENCE : KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 20,125,1941 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - duck DOSE/DURATION : 79200 ug/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) REFERENCE : VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 54(5),64,1978 *** END OF RECORD ***