*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SM9490000
CHEMICAL NAME           : Phenol,
                          4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoqu
                          inolinyl)methyl)-2-(4 -((1,2,3,4-
                          tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)met
                          hyl)phenoxy)-, (R-(R*,R*))-
CAS REGISTRY NUMBER     : 524-17-4
LAST UPDATED            : 198906
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C38-H44-N2-O6
MOLECULAR WEIGHT        : 624.84
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Dauricine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23,    1978-88. For
   publisher information, see ZYZAEU.  Volume(issue)/page/year: 23,182,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 185 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CYLPDN Zhongguo Yaoli Xuebao.  Acta Pharmacologica Sinica.  Chinese Journal
   of Pharmacology.  (China International Book Trading Corp., POB 2820,
   Beijing, Peop. Rep. China)  V.1-    1980-  Volume(issue)/page/year:
   7,419,1986
 
                            *** END OF RECORD ***