*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SM1225000
CHEMICAL NAME           : Phenol, m-(1-methyl-3-propyl-3-pyrrolidinyl)-
CAS REGISTRY NUMBER     : 428-37-5
BEILSTEIN REFERENCE NO. : 1373919
REFERENCE               : 5-21-02-00451 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H21-N-O
MOLECULAR WEIGHT        : 219.36
WISWESSER LINE NOTATION : T5NTJ A1 C3 CR CQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * A-2205
   * 3-(m-Hydroxyphenyl)-1-methyl-3-propylpyrrolidine
   * m-(1-Methyl-3-propyl-3-pyrrolidinyl)phenol
   * Profadol
   * Pyrrolidine, 3-(m-hydroxyphenyl)-1-methyl-3-propyl-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 62 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   18,185,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   18,185,1971
 
                            *** END OF RECORD ***