*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SN5485000
CHEMICAL NAME           : Phenothiazine, 10-(2,3-bis(dimethylamino)propyl)-,
                          fumarate
CAS REGISTRY NUMBER     : 2278-27-5
LAST UPDATED            : 198212
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H25-N3-S.xC4-H4-O4
MOLECULAR WEIGHT        : 1140.09
WISWESSER LINE NOTATION : T C666 BN ISJ B1YN1&1&1N1&1 &QV1U1VQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Aminopropazine fumarate
   * 10-(2,3-Bis(dimethylamino)propyl)phenothiazine fumarate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 151,515,1964
 
                            *** END OF RECORD ***