*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SN7186000
CHEMICAL NAME           : Phenothiazine-10-carbothioic acid,
                          S-(2-(diethylamino)ethyl) ester, hydrochloride
CAS REGISTRY NUMBER     : 1936-50-1
LAST UPDATED            : 199409
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H22-N2-O-S2.Cl-H
MOLECULAR WEIGHT        : 395.01
WISWESSER LINE NOTATION : T C666 BN ISJ BVS2N2&2 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * S-(2-(Diethylamino)ethyl) ester of phenothiazine-10-carbothioic acid  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JACSAT Journal of the American Chemical Society.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1879-  Volume(issue)/page/year: 75,4006,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 151,515,1964
 
                            *** END OF RECORD ***