*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : SO0175000 CHEMICAL NAME : Phenothiazine, 2-chloro-10-(3-(dimethylamino)propyl)-7-hydroxy- CAS REGISTRY NUMBER : 2095-62-7 BEILSTEIN REFERENCE NO. : 1021503 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C17-H19-Cl-N2-O-S MOLECULAR WEIGHT : 334.89 WISWESSER LINE NOTATION : T C666 BN ISJ B3N1&1 EG LQ COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 7-Hydroxychlorpromazine *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 119 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - body temperature decrease REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,715,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 4,2425,1965 *** END OF RECORD ***