*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : SO1050000 CHEMICAL NAME : Phenothiazine, 2-chloro-10-(3-(dimethylamino)propyl)-7-hydroxy-8-met hoxy-nor1- CAS REGISTRY NUMBER : 25946-86-5 LAST UPDATED : 199101 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C18-H21-Cl-N2-O2-S MOLECULAR WEIGHT : 364.92 WISWESSER LINE NOTATION : T C666 BN ISJ B3N1&1 EG MQ NO1 -NOR1 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 7-Hydroxy-8-methoxy-nor1-chlorpromazine *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 78 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - body temperature decrease REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,715,1973 *** END OF RECORD ***