*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : SO3675000 CHEMICAL NAME : Phenothiazine, 10-(3-(diallylamino)propyl)-2-(trifluromethyl)- CAS REGISTRY NUMBER : 63834-03-7 LAST UPDATED : 199506 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C22-H23-F3-N2-S MOLECULAR WEIGHT : 404.53 WISWESSER LINE NOTATION : T C666 BN ISJ B3N2U1&2U1 EXFFF COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * NDR A-3528 * 2-Trifluoromethyl-10-(diallylaminopropyl)phenothiazine *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1149 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - chromodacryorrhea Sense Organs and Special Senses (Eye) - ptosis Behavioral - rigidity (including catalepsy) REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 136,476,1962 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 977 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - chromodacryorrhea Sense Organs and Special Senses (Eye) - ptosis Behavioral - rigidity (including catalepsy) REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 136,476,1962 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 242 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 136,476,1962 *** END OF RECORD ***