*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SO5700000
CHEMICAL NAME           : Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-
CAS REGISTRY NUMBER     : 84-96-8
LAST UPDATED            : 199512
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C18-H22-N2-S
MOLECULAR WEIGHT        : 298.48
WISWESSER LINE NOTATION : T C666 BN ISJ B1Y1&1N1&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Alimemazine
   * Alimezine
   * Bayer 1219
   * Methylpromazine
   * 10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl-
   * Teralen
   * Trimeprazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANPBAZ Acta Neurologia et Psychiatrica Belgica.  (Brussels, Belgium)
   V.48-69, 1948-69.  For publisher information, see ANUBBR.
   Volume(issue)/page/year: 61,669,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANPBAZ Acta Neurologia et Psychiatrica Belgica.  (Brussels, Belgium)
   V.48-69, 1948-69.  For publisher information, see ANUBBR.
   Volume(issue)/page/year: 61,669,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Behavioral - antipsychotic
REFERENCE :
   DNEUD5 Developments in Neuroscience (Amsterdam).  (Elsevier Science Pub.
   Co., Inc., 52 Vanderbilt Ave., New York, NY 10017)  V.1-    1977-
   Volume(issue)/page/year: 7,45,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 33 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSCBAY Psychopharmacology Service Center, Bulletin.  (Bethesda, MD)  V.1-3,
   1961-65.  For publisher information, see PSYBB9.  Volume(issue)/page/year:
   2,17,1963

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X4969
       No. of Facilities: 32 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 333 (estimated)
       No. of Female Employees: 227 (estimated)

 
                            *** END OF RECORD ***