*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SO6150000
CHEMICAL NAME           : Phenothiazine,
                          10-(3-(dimethylamino)-2-methylpropyl)-2-methoxy-,
                          hydrochloride
CAS REGISTRY NUMBER     : 1236-99-3
LAST UPDATED            : 199707
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C19-H24-N2-O-S.Cl-H
MOLECULAR WEIGHT        : 364.97
WISWESSER LINE NOTATION : T C666 BN ISJ B1Y1&1N1&1 EO1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 10-(3-Dimethylamino-2-methylpropyl)-2-methoxyphenothiazine hydrochloride
   * Levomepromazine hydrochloride
   * Levomepromazinium chloride
   * Levopromazine hydrochloride
   * Methoxy-3 (dimethylamino-3 methyl-2 propyl)-10 phenothiazine  
   hydrochloride
   * Neurocil
   * Nozinan hydrochloride
   * 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,beta-trimethyl-,  
   monohydrochloride, (R)-
   * 7044 RP hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 380 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CKFRAY Ceskoslovenska Farmacie.  (PNS-Ustredni Expedice a Dovoz Tisku,
   Kafkova 19, 160 00 Prague 6, Czechoslovakia)  V.1-    1952-
   Volume(issue)/page/year: 15,455,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 135 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 160,1852,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 360 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 155,1029,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   19,87,1962
 
                            *** END OF RECORD ***