*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : SP0875000 CHEMICAL NAME : Phenothiazine, 2-methoxy-10-(2-(1-methyl-2-piperidyl)ethyl)- CAS REGISTRY NUMBER : 14759-04-7 BEILSTEIN REFERENCE NO. : 6118065 REFERENCE : 4-27-00-02038 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C21-H26-N2-O-S MOLECULAR WEIGHT : 354.55 WISWESSER LINE NOTATION : T C666 BN ISJ EO1 B2- BT6NTJ A1 SYNONYMS/TRADE NAMES : * KS-33 * 2-Methoxy-10-(2-(1-methyl-2-piperidyl)ethyl)phenothiazine * 3-Methoxy-10-(2'-(N-methylpiperidyl-2')-ethyl)phenothiazine * Oxyridazine * 10H-Phenothiazine, 2-methoxy-10-(2-(1-methyl-2-piperidyl)ethyl)- *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1130 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,27,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 760 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIGZAY Niigata Igakkai Zasshi. Niigata Medical Journal. (Niigata Igakkai, 1, Asahi-machi, Niigata 951, Japan) V.60- 1946- Volume(issue)/page/year: 82,607,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 516 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold REFERENCE : NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 65(2),104S,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 42 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold REFERENCE : NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 65(2),104S,1969 *** END OF RECORD ***