*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SY9330000
CHEMICAL NAME           : Phosphine oxide,
                          bis(1-aziridinyl)(hexahydro-1H-azepin-1-yl)-
CAS REGISTRY NUMBER     : 18144-64-4
BEILSTEIN REFERENCE NO. : 1313950
REFERENCE               : 5-20-04-00069 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H20-N3-O-P
MOLECULAR WEIGHT        : 229.30
WISWESSER LINE NOTATION : T7NTJ APO&- AT3NTJ&- AT3NTJ
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 1H-Azepine, (bis(1-aziridinyl)phosphinyl)hexahydro-
   * Bis(1-aziridinyl)(hexahydro-1H-azepin-1-yl)phosphine oxide
   * (Bis(1-aziridinyl)phosphinyl)hexahydro-1H-azepine
   * Diaziridinylhexamethyleneiminophosphine oxide
   * ENT-50716
   * Hexahydroazepinylbis(aziridinyl)phosphine oxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#06108
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Parenteral
TEST SYSTEM             : Insect - not otherwise specified
DOSE/DURATION           : 24 mmol/L
REFERENCE :
   CNJGA8 Canadian Journal of Genetics and Cytology.  (National Research
   Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6,
   Canada)  V.1-    1959-  Volume(issue)/page/year: 11,648,1969
 
TYPE OF TEST            : Dominant lethal test
ROUTE OF EXPOSURE       : Parenteral
TEST SYSTEM             : Insect - not otherwise specified
DOSE/DURATION           : 24 mmol/L
REFERENCE :
   CNJGA8 Canadian Journal of Genetics and Cytology.  (National Research
   Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6,
   Canada)  V.1-    1959-  Volume(issue)/page/year: 11,648,1969
 
                            *** END OF RECORD ***