*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SZ5383000
CHEMICAL NAME           : Phosphonic acid, methylenebis-, tetrasodium salt
CAS REGISTRY NUMBER     : 6145-29-5
LAST UPDATED            : 199710
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C-H2-O6-P2.4Na
MOLECULAR WEIGHT        : 263.93
SYNONYMS/TRADE NAMES :
   * MDP sodium
   * Medronic acid, sodium salt
   * Methanebisphosphonic acid, sodium salt
   * Methanediphosphonic acid, sodium salt
   * Methylenebis(phosphonic acid) sodium salt
   * Methylenebisphosphonic acid tetrasodium salt
   * Methylenediphosphonic acid, sodium salt
   * Sodium methylenediphosphonate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 67 mg/kg
TOXIC EFFECTS :
   Cardiac - other changes
   Behavioral - muscle contraction or spasticity
   Liver - other changes
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 5,2467,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - structural or functional change in trachea
   or bronchi
   Liver - other changes
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 5,2467,1977

                          *** STATUS IN U.S. ***
 
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***