*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SZ5790000
CHEMICAL NAME           : Phosphinic amide,
                          P,P-bis(1-aziridinyl)-N-(1-adamantyl)-
CAS REGISTRY NUMBER     : 53743-43-4
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H24-N3-O-P
MOLECULAR WEIGHT        : 281.38
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * P,P-Bis(1-aziridinyl)-N-(1-adamantyl)-phosphinic amide
   * Phosphinic amide, P,P-bis(1-aziridinyl)-N-tricyclo(3.3.1.1(sup  
   3,7))dec-1-yl-
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 50 mg/kg
SEX/DURATION            : male 5 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 21,143,1978
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 50 mg/kg
SEX/DURATION            : male 5 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 21,143,1978
 
                            *** END OF RECORD ***