*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SZ0180400
CHEMICAL NAME           : Phosphine oxide, (3-(dimethylamino)propyl)diphenyl-
CAS REGISTRY NUMBER     : 962-95-8
BEILSTEIN REFERENCE NO. : 2740877
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H22-N-O-P
MOLECULAR WEIGHT        : 287.37
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (3-(Dimethylamino)propyl)diphenylphosphine oxide
   * 1-Propanamine, 3-(diphenylphosphinyl)-N,N-dimethyl-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 54,1063,1965
 
                            *** END OF RECORD ***