*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SZ5990200
CHEMICAL NAME           : Phosphinothioic amide,
                          P,P-bis(1-aziridinyl)-N-cyclohexyl-
CAS REGISTRY NUMBER     : 3054-21-5
BEILSTEIN REFERENCE NO. : 1346167
REFERENCE               : 5-20-01-00130 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H20-N3-P-S
MOLECULAR WEIGHT        : 245.36
WISWESSER LINE NOTATION : T3NTJ APS&M- AL6TJ&- AT3NTJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * P,P-Bis(1-aziridinyl)-N-cyclohexylphosphinothioic amide
   * N,N'-Di-(ethyleneimide)-N''-cyclohexylamide of thiophosphoric acid
   * ENT 62488
   * Hexaphosphamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 105 mg/kg
TOXIC EFFECTS :
   Blood - other hemolysis with or without anemia
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   HAEMBY Haematologia.  (Kultura, POB 149, H-1389 Budapest, Hungary)  V.1-
   1967-  Volume(issue)/page/year: 11,115,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : >316 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EESADV Ecotoxicology and Environmental Safety.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1977-  Volume(issue)/page/year:
   6,149,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 12,355,1983
 
                            *** END OF RECORD ***