*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : SZ6116000
CHEMICAL NAME : Phospholipase C
CAS REGISTRY NUMBER : 9001-86-9
LAST UPDATED : 198706
DATA ITEMS CITED : 3
COMPOUND DESCRIPTOR : Drug
Natural Product
SYNONYMS/TRADE NAMES :
* E.C. 3.1.4.3
* Lecithinase C
* Lipophosphodiesterase
* Phosphotidase C
* PLC
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SJCLAY Scandinavian Journal of Clinical and Laboratory Investigation.
(Blackwell Scientific Pub. Inc., 52 Beacon St., Boston, MA 02108) V.1-
1949- Volume(issue)/page/year: 36,553,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 450 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SJCLAY Scandinavian Journal of Clinical and Laboratory Investigation.
(Blackwell Scientific Pub. Inc., 52 Beacon St., Boston, MA 02108) V.1-
1949- Volume(issue)/page/year: 42,239,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - domestic
DOSE/DURATION : 200 ug/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - chronic pulmonary edema
Gastrointestinal - changes in structure or function of salivary glands
Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
SJCLAY Scandinavian Journal of Clinical and Laboratory Investigation.
(Blackwell Scientific Pub. Inc., 52 Beacon St., Boston, MA 02108) V.1-
1949- Volume(issue)/page/year: 43,445,1983
*** END OF RECORD ***