*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : SZ6190000 CHEMICAL NAME : Phosphonamidic acid, p-(1-aziridinyl)-N-2-pyridyl-, p-((bis(1-aziridinyl)phosphinyl)oxy) phenyl ester CAS REGISTRY NUMBER : 34180-25-1 BEILSTEIN REFERENCE NO. : 0463320 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C17-H21-N5-O4-P2 MOLECULAR WEIGHT : 421.37 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * A-263 * N-(2-Pyridyl)triethylenetetraamide p-phenylenediphosphoric acid *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 92 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 6,145,1971 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 62 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 6,145,1971 *** END OF RECORD ***