*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SZ6479000
CHEMICAL NAME           : Phosphonic acid,
                          (1-(acetyloxy)-2,2,2-trichloroethyl)-, diphenyl ester
CAS REGISTRY NUMBER     : 74548-80-4
LAST UPDATED            : 199603
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C16-H14-Cl3-O5-P
MOLECULAR WEIGHT        : 423.62
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * (1-(Acetyloxy)-2,2,2-trichloroethyl)phosphonic acid diphenyl ester
   * Aphos
   * O,O-Diphenyl (1-acetoxy-2,2,2-trichloroethyl)phosphonate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3280 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZSRSBX Zashchita Rastenii (Moscow).  Plant Protection.  (V/O Mezhdunarodnaya
   Kniga, 113095 Moscow, USSR)  V.11-    1966- Volume(issue)/page/year:
   (6),36,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2134 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 50(3),57,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1720 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZSRSBX Zashchita Rastenii (Moscow).  Plant Protection.  (V/O Mezhdunarodnaya
   Kniga, 113095 Moscow, USSR)  V.11-    1966- Volume(issue)/page/year:
   (6),36,1985
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1750 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   CUTOEX Current Toxicology.  (Nova Science Publishers, Inc., 6080 Jericho
   Turnpike, Suite 207, Commack, NY  11725)  V.1    1993-
   Volume(issue)/page/year: 1,185,1993
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 368 mg/kg
SEX/DURATION            : female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - other effects to embryo
REFERENCE :
   CUTOEX Current Toxicology.  (Nova Science Publishers, Inc., 6080 Jericho
   Turnpike, Suite 207, Commack, NY  11725)  V.1    1993-
   Volume(issue)/page/year: 1,185,1993
 
                            *** END OF RECORD ***