*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SZ6790000
CHEMICAL NAME           : Phosphonic acid,
                          ((3-(bis(2-chloroethyl)amino)-4-methylphenyl)hydroxym
                          ethylene)bis-
CAS REGISTRY NUMBER     : 106871-13-0
LAST UPDATED            : 199410
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C12-H19-Cl2-N-O7-P2
MOLECULAR WEIGHT        : 422.16
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 3-(Bis(2-chloroethyl)amino)-4-methylphenyl-hydroxymethanbiphosphonic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 88 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
   Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018)  V.1- 1983- 
   Volume(issue)/page/year: 6,67,1988
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 500 ug/plate
REFERENCE :
   INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
   Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018)  V.1- 1983- 
   Volume(issue)/page/year: 6,67,1988
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 1250 ug/tube
REFERENCE :
   INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
   Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018)  V.1- 1983- 
   Volume(issue)/page/year: 6,67,1988
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION           : 1250 ug/plate
REFERENCE :
   INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
   Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018)  V.1- 1983- 
   Volume(issue)/page/year: 6,67,1988
 
                            *** END OF RECORD ***