*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : SZ7890000
CHEMICAL NAME : Phosphonic acid, (1,2-epoxypropyl)-, (1R,2S)-(-)-
CAS REGISTRY NUMBER : 23155-02-4
BEILSTEIN REFERENCE NO. : 1680831
REFERENCE : 5-18-12-00526 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C3-H7-O4-P
MOLECULAR WEIGHT : 138.07
WISWESSER LINE NOTATION : T3OTJ BPQQO C1
COMPOUND DESCRIPTOR : Drug
Mutagen
Natural Product
SYNONYMS/TRADE NAMES :
* 883A
* Antibiotic 833A
* Fosfocina
* Fosfomycin
* Fosfonomycin
* (2R-cis)-(3-Methyloxiranyl)phosphonic acid
* MK-955
* Phosphomycin
* Phosphonic acid, (3-methyloxiranyl)-, (2R-cis)-
* Phosphonomycin
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca
Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 6,426,1981
** MUTATION DATA **
TYPE OF TEST : Phage inhibition capacity
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 10 ug/plate
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
43,2819,1983
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Microorganism - not otherwise specified
DOSE/DURATION : 10 gm/L
REFERENCE :
MILEDM Microbios Letters. (Faculty Press, 88 Regent St., Cambridge, UK)
V.1- 1976- Volume(issue)/page/year: 8,27,1978
*** END OF RECORD ***