*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SZ8551500
CHEMICAL NAME           : Phosphonic acid,
                          (5-(3-fluorobenzoyl)-2,4-dihydro-3H-pyrazol-3-ylidene
                          )bis-, tetraethyl ester
CAS REGISTRY NUMBER     : 132508-17-9
LAST UPDATED            : 199409
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H27-F-N2-O7-P2
MOLECULAR WEIGHT        : 464.41
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Tetraethyl  
   (5-(3-fluorobenzoyl)-2,4-dihydro-3H-pyrazol-3-ylidene)bisphosphonate
   * U-84849
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 266,1691,1993
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 266,1691,1993
 
                            *** END OF RECORD ***