*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : SZ8570000 CHEMICAL NAME : Phosphonic acid, (1-hydroxy-2,2,2-trichloroethyl)-, diethyl ester CAS REGISTRY NUMBER : 993-86-2 BEILSTEIN REFERENCE NO. : 1812867 REFERENCE : 4-01-00-03147 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C6-H12-Cl3-O4-P MOLECULAR WEIGHT : 285.50 WISWESSER LINE NOTATION : GXGGYQPO&O2&O2 COMPOUND DESCRIPTOR : Agricultural Chemical Reproductive Effector SYNONYMS/TRADE NAMES : * Aethyltrichlorphon * ETC * Ethanephosphonic acid, 2,2,2-trichloro-1-hydroxy-, diethyl ester * Ethyl trichlorfon * Ethyltrichlorphon * 1-Hydroxy-2,2,2-trichloroethyl diethyl phosphonite * (1-Hydroxy-2,2,2-trichloroethyl)phosphonic acid diethyl ester *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1955- Volume(issue)/page/year: 22,565,1976 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE : 240 mg/kg SEX/DURATION : female 9 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - other developmental abnormalities REFERENCE : ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1955- Volume(issue)/page/year: 22,565,1976 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE : 960 mg/kg SEX/DURATION : female 9 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1955- Volume(issue)/page/year: 22,565,1976 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - guinea pig DOSE : 518 mg/kg SEX/DURATION : female 42-44 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - Central Nervous System REFERENCE : NEREDZ Neurochemical Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.1- 1976- Volume(issue)/page/year: 19,569,1994 *** END OF RECORD ***