*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SZ9066000
CHEMICAL NAME           : Phosphonic acid, methyl-,
                          (2-(bis(1-methylethyl)amino)ethyl) ethyl ester
CAS REGISTRY NUMBER     : 71840-26-1
BEILSTEIN REFERENCE NO. : 2444021
LAST UPDATED            : 199612
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C11-H26-N-O3-P
MOLECULAR WEIGHT        : 251.35
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * O-Ethyl-O'-(2-diisopropylaminoethyl)methylphosphonate
   * Methylphosphonic acid (2-(bis(1-methylethyl)amino)ethyl) ethyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 gm/15M
REACTION SEVERITY       : Moderate
REFERENCE :
   IAEC** Interagency Collaborative Group on Environmental Carcinogenesis,
   National Cancer Institute, Memorandum, June 17, 1974
   Volume(issue)/page/year: 17JUN1974
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 200 mg/15M
REACTION SEVERITY       : Mild
REFERENCE :
   IAEC** Interagency Collaborative Group on Environmental Carcinogenesis,
   National Cancer Institute, Memorandum, June 17, 1974
   Volume(issue)/page/year: 17JUN1974
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 204 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IAEC** Interagency Collaborative Group on Environmental Carcinogenesis,
   National Cancer Institute, Memorandum, June 17, 1974
   Volume(issue)/page/year: 17JUN1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 164 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IAEC** Interagency Collaborative Group on Environmental Carcinogenesis,
   National Cancer Institute, Memorandum, June 17, 1974
   Volume(issue)/page/year: 17JUN1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 11400 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IAEC** Interagency Collaborative Group on Environmental Carcinogenesis,
   National Cancer Institute, Memorandum, June 17, 1974
   Volume(issue)/page/year: 17JUN1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : 1186 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - structural change in nerve or sheath
REFERENCE :
   TOXID9 Toxicologist.  (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,
   Akron, OH 44311) V.1-    1981-  Volume(issue)/page/year: 5,195,1985
 
                            *** END OF RECORD ***