*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SZ9570000
CHEMICAL NAME           : Phosphonic acid, (3-methyloxiranyl)-, (2R-cis)-,
                          compd. with 2-amino-2-(hydroxymethyl)-1,3-
                          propanediol (1:1)
CAS REGISTRY NUMBER     : 78964-85-9
LAST UPDATED            : 199403
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C4-H11-N-O3.C3-H7-O4-P
MOLECULAR WEIGHT        : 259.23
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Fosfomycin compd. with trometamol
   * Fosfomycin trometamol salt
   * Monuril
   * Tromethamine-fosfomycin
   * Z 1282
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   13,77,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   13,77,1988
 
                            *** END OF RECORD ***