*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TA8225000
CHEMICAL NAME           : Phosphonofluoridic acid, methyl-, cyclohexyl ester
CAS REGISTRY NUMBER     : 329-99-7
OTHER CAS REGISTRY NOS. : 74192-15-7
BEILSTEIN REFERENCE NO. : 2327087
LAST UPDATED            : 199706
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C7-H14-F-O2-P
MOLECULAR WEIGHT        : 180.18
WISWESSER LINE NOTATION : L6TJ AOPO&F1
SYNONYMS/TRADE NAMES :
   * CMPF
   * Cyclohexyl methylphosphonofluoridate
   * EA 1212
   * GF (chemical warfare agent)
   * Methyl cyclohexylfluorophosphonate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 225 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CJPPA3 Canadian Journal of Physiology and Pharmacology.  (National Research
   Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6,
   Canada)  V.42-    1964-  Volume(issue)/page/year: 44,745,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - coma
   Gastrointestinal - nausea or vomiting
REFERENCE :
   SCJUAD Science Journal.  (London, UK)  V.1-7, 1965-71.  For publisher
   information, see NWSCAL.  Volume(issue)/page/year: 3(4),33,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - coma
   Gastrointestinal - nausea or vomiting
REFERENCE :
   SCJUAD Science Journal.  (London, UK)  V.1-7, 1965-71.  For publisher
   information, see NWSCAL.  Volume(issue)/page/year: 3(4),33,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 100 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CJPPA3 Canadian Journal of Physiology and Pharmacology.  (National Research
   Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6,
   Canada)  V.42-    1964-  Volume(issue)/page/year: 44,745,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 130 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CJPPA3 Canadian Journal of Physiology and Pharmacology.  (National Research
   Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6,
   Canada)  V.42-    1964-  Volume(issue)/page/year: 46,109,1968
 
                            *** END OF RECORD ***