*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TC6125000
CHEMICAL NAME           : Phosphoric acid, 2-ethylhexyl diphenyl ester
CAS REGISTRY NUMBER     : 1241-94-7
BEILSTEIN REFERENCE NO. : 2568983
REFERENCE               : 4-06-00-00718 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 15
MOLECULAR FORMULA       : C20-H27-O4-P
MOLECULAR WEIGHT        : 362.44
WISWESSER LINE NOTATION : 4Y2&1OPO&OR&OR
SYNONYMS/TRADE NAMES :
   * Diphenyl 2-ethylhexyl phosphate
   * (2-Ethylhexyl)-difenylfosfat
   * 2-Ethylhexyl diphenylphosphate
   * 1-Hexanol, 2-ethyl-, ester with diphenyl phosphate
   * Santicizer 141
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206227
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 930 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
   Behavioral - tremor
   Behavioral - muscle weakness
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206227
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 218 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IPSTB3 International Polymer Science and Technology.  (Rapra Technology
   Ltd., Shawbury, Shrewsbury, Shropshire SY4 4NR, UK) Volume(issue)/page/year:
   3,93,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >7900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   41,291,1977
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 272 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information, see AEHLAU.
   Volume(issue)/page/year: 8,170,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   41,291,1977
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 437 gm/kg/2Y-C
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information, see AEHLAU.
   Volume(issue)/page/year: 8,170,1953

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-RUSSIA:STEL 0.5 mg/m3;Skin JAN 1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 84203
       No. of Facilities: 587 (estimated)
       No. of Industries: 20
       No. of Occupations: 16
       No. of Employees: 11432 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 84203
       No. of Facilities: 1223 (estimated)
       No. of Industries: 33
       No. of Occupations: 28
       No. of Employees: 21161 (estimated)
       No. of Female Employees: 4366 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   47,26992,82

   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA Section 8(e) Risk Notification, 8EHQ-0193-8695;8EHQ-0892-9290
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***