*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TE6130000
CHEMICAL NAME           : Phosphorofluoridic acid, disodium salt
CAS REGISTRY NUMBER     : 10163-15-2
LAST UPDATED            : 199510
DATA ITEMS CITED        : 13
MOLECULAR FORMULA       : F-O3-P.2Na
MOLECULAR WEIGHT        : 143.95
WISWESSER LINE NOTATION : .NA2.P-F-O3
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Disodium fluorophosphate
   * Disodium monofluorophosphate
   * Disodium phosphorofluoridate
   * Sodium fluorophosphate (Na2PO3F)
   * Sodium monofluorophosphate
   * Sodium phosphorofluoridate
   * Sodium phosphorofluridate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 570 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JDREAF Journal of Dental Research.  (International Assoc. for Dental
   Research, 734 15th St., NW, Suite 809, Washington, DC 20005)  V.1-    1919-
   Volume(issue)/page/year: 29,529,1950
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 220 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JDREAF Journal of Dental Research.  (International Assoc. for Dental
   Research, 734 15th St., NW, Suite 809, Washington, DC 20005)  V.1-    1919-
   Volume(issue)/page/year: 29,529,1950
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 710 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CAREBK Caries Research.  (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY
   10003)  V.1-    1967-  Volume(issue)/page/year: 12,177,1978
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Dominant lethal test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 60 mmol/L
REFERENCE :
   GENTAE Genetics.  (Genetics Business Office, POB 64025, Baltimore, MD 21264)
    V.1-    1916-  Volume(issue)/page/year: 87,67,1977

                              *** REVIEWS ***
 
   IARC Cancer Review:Animal Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 27,237,1982

   IARC Cancer Review:Human Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 27,237,1982

   IARC Cancer Review:Group 3
   IMSUDL IARC Monographs, Supplement.  (WHO Publications Centre USA, 49
   Sheridan Ave., Albany, NY 12210)  No.1-    1979-  Volume(issue)/page/year:
   7,208,1987

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   OSHA PEL (Gen Indu):8H TWA 2.5 mg(F)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 2.5 mg(F)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 2.5 mg(F)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 2.5 mg(F)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO FLUORIDES, INORGANIC-air:10H TWA 2.5 mg(F)/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X2356
       No. of Facilities: 44 (estimated)
       No. of Industries: 1
       No. of Occupations: 5
       No. of Employees: 16999 (estimated)
       No. of Female Employees: 15598 (estimated)

 
                            *** END OF RECORD ***