*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TF0175000
CHEMICAL NAME           : Phosphorothioic acid, O-(2,5-dichloro-4-iodophenyl)
                          O,O-dimethyl ester
CAS REGISTRY NUMBER     : 18181-70-9
BEILSTEIN REFERENCE NO. : 1885795
LAST UPDATED            : 199710
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : C8-H8-Cl2-I-O3-P-S
MOLECULAR WEIGHT        : 412.99
WISWESSER LINE NOTATION : IR BG EG DOPS&O1&O1
COMPOUND DESCRIPTOR     : Agricultural Chemical
SYNONYMS/TRADE NAMES :
   * Alfacron
   * C-9491
   * Ciba C-9491
   * Ciba-Geigy C-9491
   * Compound C-9491
   * O-(2,5-Dichloro-4-iodophenyl) O,O-dimethyl phosphorothioate
   * O,O-Dimethyl-O-(2,5-dichlor-4-jodphenyl)-thionophosphat
   * O,O-Dimethyl-O-(2,5-dichlor-4-jodphenyl)-monothiophosphat
   * O,O-Dimethyl-O-2,5-dichloro-4-iodophenyl thiophosphate
   * ENT 27408
   * Iodofenphos
   * Iodophenphos
   * Iodophos
   * Jodfenphos
   * NSC 190998
   * Monocron 9491
   * Nuvanol N
   * OMS-1211
   * Phenol, 3,4-dichloro-, O-ester with O-methyl methylphosphoramidothioate
   * Trix
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2330 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JTCEEM Journal de Toxicologie Clinique et Experimentale.  (SPPIF, B.P.22,
   F-41353 Vineuil, France) V.5-    1985-  Volume(issue)/page/year:
   6(3),175,1986
 
TYPE OF TEST            : LC - Lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >246 mg/m3/6H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd,
   eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year:
   A239,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SPEADM Special Publication of the Entomological Society of America.  (4603
   Calvert Rd., College Park, MD 20740)  Volume(issue)/page/year: 78-1,45,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag
   New York, Inc., 1971  Volume(issue)/page/year: -,335,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel,"
   Perkow, W., Berlin, Verlag Paul Parey, 1971-1976  Volume(issue)/page/year:
   -,-,1971/1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel,"
   Perkow, W., Berlin, Verlag Paul Parey, 1971-1976  Volume(issue)/page/year:
   -,-,1971/1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel,"
   Perkow, W., Berlin, Verlag Paul Parey, 1971-1976  Volume(issue)/page/year:
   -,-,1971/1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel,"
   Perkow, W., Berlin, Verlag Paul Parey, 1971-1976  Volume(issue)/page/year:
   -,-,1971/1976
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 19 gm/kg/43W-I
TOXIC EFFECTS :
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - true cholinesterase
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - transaminases
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 45(11),75,1980

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-RUSSIA:STEL 0.5 mg/m3 JAN 1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X4724
       No. of Facilities: 9 (estimated)
       No. of Industries: 1
       No. of Occupations: 4
       No. of Employees: 163 (estimated)
       No. of Female Employees: 120 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***