*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TF1590000
CHEMICAL NAME           : Phosphorothioic acid, O,O-diethyl
                          O-(2,5-dichloro-4-(methylthio)phenyl) ester
CAS REGISTRY NUMBER     : 21923-23-9
OTHER CAS REGISTRY NOS. : 51052-59-6
BEILSTEIN REFERENCE NO. : 2003497
LAST UPDATED            : 199612
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C11-H15-Cl2-O3-P-S2
MOLECULAR WEIGHT        : 361.25
WISWESSER LINE NOTATION : 2OPS&O2&OR BG EG DS1
COMPOUND DESCRIPTOR     : Agricultural Chemical
SYNONYMS/TRADE NAMES :
   * Celamerck S-2957
   * CELA S-2957
   * Celathion
   * Chlorthiophos I
   * CM S 2957
   * O-(Dichloro(methylthio)phenyl) O,O-diethyl phosphorothioate (3 isomers)
   * O,O-Diethyl-O-2,4,5-dichloro-(methylthio)phenyl thionophosphate
   * ENT 27635
   * NSC 195164
   * OMS 1342
   * Phosphorothioic acid, O-(2,5-dichloro-4-(methylthio)phenyl) O,O-diethyl  
   ester
   * S 2957
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AHRTAN Arhiv za Higijenu Rada i Toksikologiju.  Archives of Industrial
   Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade,
   Yugoslavia)  V.7-    1956-  Volume(issue)/page/year: 27,3,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 58 mg/kg
TOXIC EFFECTS :
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - reactivates cholinesterase
REFERENCE :
   AHRTAN Arhiv za Higijenu Rada i Toksikologiju.  Archives of Industrial
   Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade,
   Yugoslavia)  V.7-    1956-  Volume(issue)/page/year: 27,3,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 141 mg/kg
TOXIC EFFECTS :
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - reactivates cholinesterase
REFERENCE :
   AHRTAN Arhiv za Higijenu Rada i Toksikologiju.  Archives of Industrial
   Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade,
   Yugoslavia)  V.7-    1956-  Volume(issue)/page/year: 27,3,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - reactivates cholinesterase
REFERENCE :
   AHRTAN Arhiv za Higijenu Rada i Toksikologiju.  Archives of Industrial
   Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade,
   Yugoslavia)  V.7-    1956-  Volume(issue)/page/year: 27,3,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 31 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de
   Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France)
   V.1-  1947-  Volume(issue)/page/year: 36,31,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 58 mg/kg
TOXIC EFFECTS :
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - reactivates cholinesterase
REFERENCE :
   AHRTAN Arhiv za Higijenu Rada i Toksikologiju.  Archives of Industrial
   Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade,
   Yugoslavia)  V.7-    1956-  Volume(issue)/page/year: 27,3,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - food intake (animal)
REFERENCE :
   AHRTAN Arhiv za Higijenu Rada i Toksikologiju.  Archives of Industrial
   Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade,
   Yugoslavia)  V.7-    1956-  Volume(issue)/page/year: 27,3,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AHRTAN Arhiv za Higijenu Rada i Toksikologiju.  Archives of Industrial
   Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade,
   Yugoslavia)  V.7-    1956-  Volume(issue)/page/year: 27,3,1976
 
                            *** END OF RECORD ***