*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TF1590000 CHEMICAL NAME : Phosphorothioic acid, O,O-diethyl O-(2,5-dichloro-4-(methylthio)phenyl) ester CAS REGISTRY NUMBER : 21923-23-9 OTHER CAS REGISTRY NOS. : 51052-59-6 BEILSTEIN REFERENCE NO. : 2003497 LAST UPDATED : 199612 DATA ITEMS CITED : 8 MOLECULAR FORMULA : C11-H15-Cl2-O3-P-S2 MOLECULAR WEIGHT : 361.25 WISWESSER LINE NOTATION : 2OPS&O2&OR BG EG DS1 COMPOUND DESCRIPTOR : Agricultural Chemical SYNONYMS/TRADE NAMES : * Celamerck S-2957 * CELA S-2957 * Celathion * Chlorthiophos I * CM S 2957 * O-(Dichloro(methylthio)phenyl) O,O-diethyl phosphorothioate (3 isomers) * O,O-Diethyl-O-2,4,5-dichloro-(methylthio)phenyl thionophosphate * ENT 27635 * NSC 195164 * OMS 1342 * Phosphorothioic acid, O-(2,5-dichloro-4-(methylthio)phenyl) O,O-diethyl ester * S 2957 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 13 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea REFERENCE : AHRTAN Arhiv za Higijenu Rada i Toksikologiju. Archives of Industrial Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade, Yugoslavia) V.7- 1956- Volume(issue)/page/year: 27,3,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 58 mg/kg TOXIC EFFECTS : Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - reactivates cholinesterase REFERENCE : AHRTAN Arhiv za Higijenu Rada i Toksikologiju. Archives of Industrial Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade, Yugoslavia) V.7- 1956- Volume(issue)/page/year: 27,3,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 141 mg/kg TOXIC EFFECTS : Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - reactivates cholinesterase REFERENCE : AHRTAN Arhiv za Higijenu Rada i Toksikologiju. Archives of Industrial Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade, Yugoslavia) V.7- 1956- Volume(issue)/page/year: 27,3,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - reactivates cholinesterase REFERENCE : AHRTAN Arhiv za Higijenu Rada i Toksikologiju. Archives of Industrial Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade, Yugoslavia) V.7- 1956- Volume(issue)/page/year: 27,3,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 31 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 36,31,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 58 mg/kg TOXIC EFFECTS : Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - reactivates cholinesterase REFERENCE : AHRTAN Arhiv za Higijenu Rada i Toksikologiju. Archives of Industrial Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade, Yugoslavia) V.7- 1956- Volume(issue)/page/year: 27,3,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - chicken DOSE/DURATION : 45 mg/kg TOXIC EFFECTS : Behavioral - ataxia Behavioral - food intake (animal) REFERENCE : AHRTAN Arhiv za Higijenu Rada i Toksikologiju. Archives of Industrial Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade, Yugoslavia) V.7- 1956- Volume(issue)/page/year: 27,3,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - quail DOSE/DURATION : 45 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AHRTAN Arhiv za Higijenu Rada i Toksikologiju. Archives of Industrial Hygiene and Toxicology. (Jugoslovenska Knjiga, POB 36, YU-11001 Belgrade, Yugoslavia) V.7- 1956- Volume(issue)/page/year: 27,3,1976 *** END OF RECORD ***